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Host defense against systemic infection with Streptococcus pneumoniae is impaired in E-, P-, and E-/P-selectin-deficient mice.

Endothelial selectins mediate rolling of leukocytes on endothelium, a crucial step for leukocyte firm adhesion and emigration into sites of tissue injury and infection. To characterize the role of the endothelial selectins during bacterial sepsis in vivo, Streptococcus pneumoniae (1-10 x 10(6) colon...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Munoz, F M, Hawkins, E P, Bullard, D C, Beaudet, A L, Kaplan, S L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508402/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9329976/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119744
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