Host defense against systemic infection with Streptococcus pneumoniae is impaired in E-, P-, and E-/P-selectin-deficient mice.

Endothelial selectins mediate rolling of leukocytes on endothelium, a crucial step for leukocyte firm adhesion and emigration into sites of tissue injury and infection. To characterize the role of the endothelial selectins during bacterial sepsis in vivo, Streptococcus pneumoniae (1-10 x 10(6) colon...

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Main Authors: Munoz, F M, Hawkins, E P, Bullard, D C, Beaudet, A L, Kaplan, S L
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1997
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC508402/
https://ncbi.nlm.nih.gov/pubmed/9329976
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