YAP Inhibition by Resveratrol via Activation of AMPK Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine

Resveratrol, a natural polyphenol present in most plants, inhibits the growth of numerous cancers both in vitro and in vivo. Aberrant expression of YAP has been reported to activate multiple growth-regulatory pathways and confer anti-apoptotic abilities to many cancer cells. However, the role of res...

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Vydáno v:Nutrients
Hlavní autoři: Jiang, Zhengdong, Chen, Xin, Chen, Ke, Sun, Liankang, Gao, Luping, Zhou, Cancan, Lei, Meng, Duan, Wanxing, Wang, Zheng, Ma, Qingyong, Ma, Jiguang
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083973/
https://ncbi.nlm.nih.gov/pubmed/27669292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu8100546
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