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Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer.

Both rheumatoid arthritis and animal models of autoimmune arthritis are characterized by hyperactivation of synovial cells and hyperplasia of the synovial membrane. The activated synovial cells produce inflammatory cytokines and degradative enzymes that lead to destruction of cartilage and bones. Ef...

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Bibliographic Details
Main Authors: Zhang, H, Yang, Y, Horton, J L, Samoilova, E B, Judge, T A, Turka, L A, Wilson, J M, Chen, Y
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC508384/
https://ncbi.nlm.nih.gov/pubmed/9329958
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