Therapy for persistent hyperinsulinemic hypoglycemia of infancy. Understanding the responsiveness of beta cells to diazoxide and somatostatin.

The neonatal disorder persistent hyperinsulinemic hypoglycemia of infancy (PHHI) arises as the result of mutations in the subunits that form the ATP-sensitive potassium (KATP) channel in pancreatic beta cells, leading to insulin hypersecretion. Diazoxide (a specific KATP channel agonist in normal be...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Kane, C, Lindley, K J, Johnson, P R, James, R F, Milla, P J, Aynsley-Green, A, Dunne, M J
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1997
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508376/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9312191/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119718
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