CCL2 as a potential therapeutic target for clear cell renal cell carcinoma

We previously reported that the pVHL‐atypical PKC‐JunB pathway contributed to promotion of cell invasiveness and angiogenesis in clear cell renal cell carcinoma (ccRCC), and we detected chemokine (C‐C motif) ligand‐2 (CCL2) as one of downstream effectors of JunB. CCL2 plays a critical role in tumori...

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Vydáno v:Cancer Med
Hlavní autoři: Arakaki, Ryuichiro, Yamasaki, Toshinari, Kanno, Toru, Shibasaki, Noboru, Sakamoto, Hiromasa, Utsunomiya, Noriaki, Sumiyoshi, Takayuki, Shibuya, Shinsuke, Tsuruyama, Tatsuaki, Nakamura, Eijiro, Ogawa, Osamu, Kamba, Tomomi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Cancer Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083746/
https://ncbi.nlm.nih.gov/pubmed/27666332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.886
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