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Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling.

TNF-alpha has been shown to be an important mediator of insulin resistance linked to obesity. This cytokine induces insulin resistance, at least in part, through inhibition of the tyrosine kinase activity of the insulin receptor. Recently, a new class of compounds, the antidiabetic thiazolidinedione...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Peraldi, P, Xu, M, Spiegelman, B M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1997
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC508373/
https://ncbi.nlm.nih.gov/pubmed/9312188
Tagiau: Ychwanegu Tag
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