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Tumor necrosis factor-alpha- and hyperglycemia-induced insulin resistance. Evidence for different mechanisms and different effects on insulin signaling.

Inhibition of insulin receptor signaling by high glucose levels and by TNF-alpha was recently observed in different cell systems. The aim of the present study was to characterize the mechanism of TNF-alpha-induced insulin receptor inhibition and to compare the consequences of TNF-alpha- and hypergly...

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Main Authors: Kroder, G, Bossenmaier, B, Kellerer, M, Capp, E, Stoyanov, B, Mühlhöfer, A, Berti, L, Horikoshi, H, Ullrich, A, Häring, H
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC507207/
https://ncbi.nlm.nih.gov/pubmed/8617880
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