Store-Operated Ca(2+) Entry (SOCE) and Purinergic Receptor-Mediated Ca(2+) Homeostasis in Murine bv2 Microglia Cells: Early Cellular Responses to ATP-Mediated Microglia Activation

Microglia activation is a neuroinflammatory response to parenchymal damage with release of intracellular metabolites, e.g., purines, and signaling molecules from damaged cells. Extracellular purines can elicit Ca(2+)-mediated microglia activation involving P2X/P2Y receptors with metabotropic (P2Y) a...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Gilbert, Daniel F., Stebbing, Martin J., Kuenzel, Katharina, Murphy, Robyn M., Zacharewicz, Evelyn, Buttgereit, Andreas, Stokes, Leanne, Adams, David J., Friedrich, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083710/
https://ncbi.nlm.nih.gov/pubmed/27840602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00111
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