1,25-Dihydroxyvitamin D3 and its analogues inhibit acute myelogenous leukemia progenitor proliferation by suppressing interleukin-1beta production.

We hypothesized that 1,25-dihydroxyvitamin D3 (1,25D3) and its analogues may inhibit acute myelogenous leukemia (AML) proliferation by interrupting IL-1beta-mediated growth-stimulatory signals. The incubation of the IL-1beta- responsive AML cell line OCIM2 with 10 nM 1,25D3 reduced growth 80% in liq...

Celý popis

Podrobná bibliografie

Vydáno v:	J Clin Invest
Hlavní autoři:	Peleg, S, Qiu, H, Reddy, S, Harris, D, Van, Q, Estey, E H, Talpaz, M, Estrov, Z
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508354/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9312169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119696
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!