Heterozygosity for a defective gene for CC chemokine receptor 5 is not the sole determinant for the immunologic and virologic phenotype of HIV-infected long-term nonprogressors.

HIV-1-infected long-term nonprogressors are a heterogeneous group of individuals with regard to immunologic and virologic markers of HIV-1 disease. CC chemokine receptor 5 (CCR5) has recently been identified as an important coreceptor for HIV-1 entry into CD4+ T cells. A mutant allele of CCR5 confer...

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Main Authors: Cohen, O J, Vaccarezza, M, Lam, G K, Baird, B F, Wildt, K, Murphy, P M, Zimmerman, P A, Nutman, T B, Fox, C H, Hoover, S, Adelsberger, J, Baseler, M, Arthos, J, Davey, R T, Dewar, R L, Metcalf, J, Schwartzentruber, D J, Orenstein, J M, Buchbinder, S, Saah, A J, Detels, R, Phair, J, Rinaldo, C, Margolick, J B, Fauci, A S
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508340/
https://ncbi.nlm.nih.gov/pubmed/9294127
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