Foxp2 Controls Synaptic Wiring of Corticostriatal Circuits and Vocal Communication by Opposing Mef2C

Cortico-basal ganglia circuits are critical for speech and language and are implicated in autism spectrum disorder (ASD), in which language function can be severely affected. We demonstrate that in the striatum, the gene, Foxp2, negatively interacts with the synapse suppressor, Mef2C. We present cau...

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Detaylı Bibliyografya
Yayımlandı:Nat Neurosci
Asıl Yazarlar: Chen, Yi-Chuan, Kuo, Hsiao-Ying, Bornschein, Ulrich, Takahashi, Hiroshi, Chen, Shih-Yun, Lu, Kuan-Ming, Yang, Hao-Yu, Chen, Gui-May, Lin, Jing-Ruei, Lee, Yi-Hsin, Chou, Yun-Chia, Cheng, Sin-Jhong, Chien, Cheng-Ting, Enard, Wolfgang, Hevers, Wulf, Pääbo, Svante, Graybiel, Ann M., Liu, Fu-Chin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083203/
https://ncbi.nlm.nih.gov/pubmed/27595386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4380
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