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IRA2, an upstream negative regulator of RAS in yeast, is a RAS GTPase-activating protein.

The ras GTPase-activating protein (GAP), identified and characterized in mammalian cells, stimulates the intrinsic GTPase activity of ras proteins. We have previously proposed that the IRA genes, negative regulators of RAS genes in Saccharomyces cerevisiae, encode yeast homologs of the mammalian GAP...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Tanaka, K, Lin, B K, Wood, D R, Tamanoi, F
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1991
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50832/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1988946/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.2.468
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