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IRA2, an upstream negative regulator of RAS in yeast, is a RAS GTPase-activating protein.

The ras GTPase-activating protein (GAP), identified and characterized in mammalian cells, stimulates the intrinsic GTPase activity of ras proteins. We have previously proposed that the IRA genes, negative regulators of RAS genes in Saccharomyces cerevisiae, encode yeast homologs of the mammalian GAP...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Tanaka, K, Lin, B K, Wood, D R, Tamanoi, F
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50832/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1988946/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.2.468
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