BCL-2 as a Therapeutic Target in Human Tubulointerstitial Inflammation

OBJECTIVE: In lupus nephritis (LuN), tubulointerstitial inflammation (TII) is associated with in situ adaptive immune cell networks that amplify local tissue damage. As patients with severe TII often fail conventional therapy and develop renal failure, understanding these in situ mechanisms might re...

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Veröffentlicht in:Arthritis Rheumatol
Hauptverfasser: Ko, Kichul, Wang, Jianing, Perper, Stuart, Jiang, Yulei, Yanez, Denisse, Kaverina, Natalya, Ai, Junting, Liarski, Vladimir M., Chang, Anthony, Peng, Yahui, Lan, Li, Westmoreland, Susan, Olson, Lisa, Giger, Maryellen L., Wang, Li Chun, Clark, Marcus R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083145/
https://ncbi.nlm.nih.gov/pubmed/27159593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39744
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