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Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a

Pluripotent embryonic stem cells (ESCs) self-renew or differentiate into all tissues of the developing embryo and cell-specification factors are necessary to balance gene expression. Here we delineate the function of the PHD-finger protein 5a (Phf5a) in ESC self-renewal and ascribe its role in regul...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Strikoudis, Alexandros, Lazaris, Charalampos, Trimarchi, Thomas, Neto, Antonio L. Galvao, Yang, Yan, Ntziachristos, Panagiotis, Rothbart, Scott, Buckley, Shannon, Dolgalev, Igor, Stadtfeld, Matthias, Strahl, Brian D., Dynlacht, Brian D., Tsirigos, Aristotelis, Aifantis, Iannis
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083132/
https://ncbi.nlm.nih.gov/pubmed/27749823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3424
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