Nalaganje...

Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes.

The treatment of advanced ovarian cancer with taxol is hindered by the development of drug resistance. The cellular target for taxol is the microtubule that is stabilized by the drug. Taxol preferentially binds to the beta subunit of tubulin of which there are six distinct isotypes in mammalian cell...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Kavallaris, M, Kuo, D Y, Burkhart, C A, Regl, D L, Norris, M D, Haber, M, Horwitz, S B
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC508306/
https://ncbi.nlm.nih.gov/pubmed/9276747
Oznake: Označite
Brez oznak, prvi označite!