Stimulus coupling to transcription versus secretion in pheochromocytoma cells. Convergent and divergent signal transduction pathways and the crucial roles for route of cytosolic calcium entry and protein kinase C.

How do chromaffin cell secretory stimuli program resynthesis of secreted peptides and amines? We previously showed that the physiologic nicotinic cholinergic signal for secretion also activates the biosynthesis of chromogranin A, the major protein released with catecholamines. Here, we examine signa...

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Pubblicato in:	J Clin Invest
Autori principali:	Tang, K, Wu, H, Mahata, S K, Mahata, M, Gill, B M, Parmer, R J, O'Connor, D T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508294/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9276735/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119630
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