Processing of chromogranin A by plasmin provides a novel mechanism for regulating catecholamine secretion

Chromogranin A (CgA) is the major soluble protein in the core of catecholamine-storage vesicles and is also distributed widely in secretory vesicles throughout the neuroendocrine system. CgA contains the sequences for peptides that modulate catecholamine release, but the proteases responsible for th...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Parmer, Robert J., Mahata, Manjula, Gong, Yun, Mahata, Sushil K., Jiang, Qijiao, O’Connor, Daniel T., Xi, Xiao-Ping, Miles, Lindsey A.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 2000
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC381423/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11018079/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI7394
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