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Palladium-Catalyzed Transannular C–H Functionalization of Alicyclic Amines

The discovery of pharmaceutical candidates is a resource-intensive enterprise that frequently requires the parallel synthesis of hundreds or even thousands of molecules. Carbon-hydrogen bonds are present in almost all pharmaceutical agents. As such, the development of selective, rapid, and efficient...

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Bibliografiset tiedot
Julkaisussa:Nature
Päätekijät: Topczewski, Joseph J., Cabrera, Pablo J., Saper, Noam I., Sanford, Melanie S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082708/
https://ncbi.nlm.nih.gov/pubmed/26886789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16957
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