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Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease‐related H109R variant
The human dimethylglycine dehydrogenase (hDMGDH) is a flavin adenine dinucleotide (FAD)‐ and tetrahydrofolate (THF)‐dependent, mitochondrial matrix enzyme taking part in choline degradation, one‐carbon metabolism and electron transfer to the respiratory chain. The rare natural variant H109R causes d...
Guardat en:
| Publicat a: | FEBS J |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5082570/ https://ncbi.nlm.nih.gov/pubmed/27486859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13828 |
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