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Molecular basis of dimethylglycine dehydrogenase deficiency associated with pathogenic variant H109R
Dimethylglycine dehydrogenase (DMGDH) is a mitochondrial matrix flavoprotein that catalyses the demethylation of dimethylglycine to form sarcosine, accompanied by the reduction of the covalently bound FAD cofactor. Electron-transfer flavoprotein reoxidizes the reduced flavin and transfers reducing e...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828353/ https://ncbi.nlm.nih.gov/pubmed/18937046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10545-008-0999-2 |
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