Interferon gamma and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators.

Human respiratory epithelium expresses inducible nitric oxide synthase (iNOS) continuously in vivo, however mechanisms responsible for maintenance of expression are not known. We show that IFNgamma is sufficient for induction of iNOS in primary human airway epithelial cells (HAEC) in vitro, and IL-4...

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Detaylı Bibliyografya

Yayımlandı:	J Clin Invest
Asıl Yazarlar:	Guo, F H, Uetani, K, Haque, S J, Williams, B R, Dweik, R A, Thunnissen, F B, Calhoun, W, Erzurum, S C
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Clinical Investigation 1997
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508255/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9259582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119598
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