Interferon gamma and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators.

Human respiratory epithelium expresses inducible nitric oxide synthase (iNOS) continuously in vivo, however mechanisms responsible for maintenance of expression are not known. We show that IFNgamma is sufficient for induction of iNOS in primary human airway epithelial cells (HAEC) in vitro, and IL-4...

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Detalhes bibliográficos
Main Authors: Guo, F H, Uetani, K, Haque, S J, Williams, B R, Dweik, R A, Thunnissen, F B, Calhoun, W, Erzurum, S C
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508255/
https://ncbi.nlm.nih.gov/pubmed/9259582
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