IL-12 Expressing oncolytic herpes simplex virus promotes anti-tumor activity and immunologic control of metastatic ovarian cancer in mice

BACKGROUND: Despite advances in surgical aggressiveness and conventional chemotherapy, ovarian cancer remains the most lethal cause of gynecologic cancer mortality; consequently there is a need for new therapeutic agents and innovative treatment paradigms for the treatment of ovarian cancer. Several...

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Bibliografski detalji
Izdano u:J Ovarian Res
Glavni autori: Thomas, Eric D., Meza-Perez, Selene, Bevis, Kerri S, Randall, Troy D., Gillespie, G. Yancey, Langford, Catherine, Alvarez, Ronald D.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082415/
https://ncbi.nlm.nih.gov/pubmed/27784340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-016-0282-3
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