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Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors
Genetically engineered, neuroattenuated herpes simplex viruses (HSVs) expressing various cytokines can improve survival when used in the treatment of experimental brain tumors. These attenuated viruses have both copies of γ(1)34.5 deleted. Recently, we demonstrated increased survival of C57BL/6 mice...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15779/ https://ncbi.nlm.nih.gov/pubmed/10681459 |
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