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Cytosolic domain of the type I interleukin-1 receptor spontaneously recruits signaling molecules to activate a proinflammatory gene.

Immediate postreceptor events activated by IL-1-IL-1R interaction remain undefined. We have initiated studies to identify candidate signal transducers that associate with the cytosolic domain (cd) of the IL-1R. Immunocomplex kinase assays demonstrated an IL-1-activated myelin basic protein kinase ac...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Singh, R, Huang, S, Guth, T, Konieczkowski, M, Sedor, J R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508206/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9218520/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119549
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