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An α-Helical Signal in the Cytosolic Domain of the Interleukin 2 Receptor β Chain Mediates Sorting Towards Degradation after Endocytosis

High-affinity IL2 receptors consist of three components, the α, β, and γ chains that are associated in a noncovalent manner. Both the β and γ chains belong to the cytokine receptor superfamily. Interleukin 2 (IL2) binds to high-affinity receptors on the cell surface and IL2-receptor complexes are in...

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Autors principals: Subtil, Agathe, Delepierre, Muriel, Dautry-Varsat, Alice
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134293/
https://ncbi.nlm.nih.gov/pubmed/9024689
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