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Accumulation of specific sterol precursors targets a MAP kinase cascade mediating cell–cell recognition and fusion
Sterols are vital components of eukaryotic cell membranes. Defects in sterol biosynthesis, which result in the accumulation of precursor molecules, are commonly associated with cellular disorders and disease. However, the effects of these sterol precursors on the metabolism, signaling, and behavior...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5081648/ https://ncbi.nlm.nih.gov/pubmed/27708165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610527113 |
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