Accumulation of specific sterol precursors targets a MAP kinase cascade mediating cell–cell recognition and fusion

Sterols are vital components of eukaryotic cell membranes. Defects in sterol biosynthesis, which result in the accumulation of precursor molecules, are commonly associated with cellular disorders and disease. However, the effects of these sterol precursors on the metabolism, signaling, and behavior...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Weichert, Martin, Lichius, Alexander, Priegnitz, Bert-Ewald, Brandt, Ulrike, Gottschalk, Johannes, Nawrath, Thorben, Groenhagen, Ulrike, Read, Nick D., Schulz, Stefan, Fleißner, André
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081648/
https://ncbi.nlm.nih.gov/pubmed/27708165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610527113
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