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Transgenic dissection of HIV genes involved in lymphoid depletion.

Transgenic mice carrying an HIV provirus, with selective deletion of all three structural genes, developed extensive lymphoid depletion which was detected not only in the spleen and lymph nodes but also in the thymus. Mice with a high level of HIV gene expression developed acute disease which result...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Tinkle, B T, Ueda, H, Ngo, L, Luciw, P A, Shaw, K, Rosen, C A, Jay, G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508162/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9202054/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119518
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