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Structural differences between the hormone and antihormone estrogen receptor complexes bound to the hormone response element.

To investigate the molecular mechanism(s) by which the estrogen receptor (ER) modulates transcription, we compared the structures of receptor complexes containing estradiol, the agonist diethylstilbestrol, and the antagonist ICI164,384. The binding of ICI164,384 to nontransformed 8-9S ER does not pr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sabbah, M, Gouilleux, F, Sola, B, Redeuilh, G, Baulieu, E E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1991
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC50816/
https://ncbi.nlm.nih.gov/pubmed/1988939
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