eIF2α phosphorylation controls thermal nociception

A response to environmental stress is critical to alleviate cellular injury and maintain cellular homeostasis. Eukaryotic initiation factor 2 (eIF2) is a key integrator of cellular stress responses and an important regulator of mRNA translation. Diverse stress signals lead to the phosphorylation of...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Khoutorsky, Arkady, Sorge, Robert E., Prager-Khoutorsky, Masha, Pawlowski, Sophie Anne, Longo, Geraldine, Jafarnejad, Seyed Mehdi, Tahmasebi, Soroush, Martin, Loren J., Pitcher, Mark H., Gkogkas, Christos G., Sharif-Naeini, Reza, Ribeiro-da-Silva, Alfredo, Bourque, Charles W., Cervero, Fernando, Mogil, Jeffrey S., Sonenberg, Nahum
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081582/
https://ncbi.nlm.nih.gov/pubmed/27698114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614047113
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