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Cristae remodeling causes acidification detected by integrated graphene sensor during mitochondrial outer membrane permeabilization
The intrinsic apoptotic pathway and the resultant mitochondrial outer membrane permeabilization (MOMP) via BAK and BAX oligomerization, cytochrome c (cytc) release, and caspase activation are well studied, but their effect on cytosolic pH is poorly understood. Using isolated mitochondria, we show th...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5081517/ https://ncbi.nlm.nih.gov/pubmed/27786282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35907 |
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