The role of transglutaminase in the rat subtotal nephrectomy model of renal fibrosis.

Tissue transglutaminase is a calcium-dependent enzyme that catalyzes the cross-linking of polypeptide chains, including those of extracellular matrix (ECM) proteins, through the formation of epsilon-(gamma-glutamyl) lysine bonds. This crosslinking leads to the formation of protein polymers that are...

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Main Authors: Johnson, T S, Griffin, M, Thomas, G L, Skill, J, Cox, A, Yang, B, Nicholas, B, Birckbichler, P J, Muchaneta-Kubara, C, Meguid El Nahas, A
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508147/
https://ncbi.nlm.nih.gov/pubmed/9185519
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