Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression

OBJECTIVE: The transcription factor cyclic AMP-responsive element-binding protein H (CREBH, encoded by Creb3l3) is highly expressed in the liver and small intestine. Hepatic CREBH contributes to glucose and triglyceride metabolism by regulating fibroblast growth factor 21 (Fgf21) expression. However...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Kikuchi, Takuya, Orihara, Kana, Oikawa, Fusaka, Han, Song-iee, Kuba, Motoko, Okuda, Kanako, Satoh, Aoi, Osaki, Yoshinori, Takeuchi, Yoshinori, Aita, Yuichi, Matsuzaka, Takashi, Iwasaki, Hitoshi, Yatoh, Shigeru, Sekiya, Motohiro, Yahagi, Naoya, Suzuki, Hiroaki, Sone, Hirohito, Nakagawa, Yoshimi, Yamada, Nobuhiro, Shimano, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081412/
https://ncbi.nlm.nih.gov/pubmed/27818935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.09.004
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