Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue

Previous work indicated that lysine-specific demethylase 1 (Lsd1) can positively regulate the oxidative and thermogenic capacities of white and beige adipocytes. Here we investigate the role of Lsd1 in brown adipose tissue (BAT) and find that BAT-selective Lsd1 ablation induces a shift from oxidativ...

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Udgivet i:Cell Rep
Main Authors: Duteil, Delphine, Tosic, Milica, Lausecker, Franziska, Nenseth, Hatice Z., Müller, Judith M., Urban, Sylvia, Willmann, Dominica, Petroll, Kerstin, Messaddeq, Nadia, Arrigoni, Laura, Manke, Thomas, Kornfeld, Jan-Wilhelm, Brüning, Jens C., Zagoriy, Vyacheslav, Meret, Michael, Dengjel, Jörn, Kanouni, Toufike, Schüle, Roland
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081406/
https://ncbi.nlm.nih.gov/pubmed/27760309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.053
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