Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat

The naked mole-rat is a subterranean rodent lacking several pain behaviors found in humans, rats, and mice. For example, nerve growth factor (NGF), an important mediator of pain sensitization, fails to produce thermal hyperalgesia in naked mole-rats. The sensitization of capsaicin-sensitive TRPV1 io...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Omerbašić, Damir, Smith, Ewan St. J., Moroni, Mirko, Homfeld, Johanna, Eigenbrod, Ole, Bennett, Nigel C., Reznick, Jane, Faulkes, Chris G., Selbach, Matthias, Lewin, Gary R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081396/
https://ncbi.nlm.nih.gov/pubmed/27732851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.035
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