Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells

Increasing evidence highlighted the role of cancer stem cells (CSCs) in the development of tumor resistance to therapy, particularly in glioblastoma (GBM). Therefore, the development of new therapies, specifically directed against GBM CSCs, constitutes an important research avenue. Considering the e...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Angeletti, Francesca, Fossati, Gianluca, Pattarozzi, Alessandra, Würth, Roberto, Solari, Agnese, Daga, Antonio, Masiello, Irene, Barbieri, Federica, Florio, Tullio, Comincini, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081386/
https://ncbi.nlm.nih.gov/pubmed/27833530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00107
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