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TCR Triggering Induces the Formation of Lck–RACK1–Actinin-1 Multiprotein Network Affecting Lck Redistribution
The initiation of T-cell signaling is critically dependent on the function of the member of Src family tyrosine kinases, Lck. Upon T-cell antigen receptor (TCR) triggering, Lck kinase activity induces the nucleation of signal-transducing hubs that regulate the formation of complex signaling network...
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Опубликовано в: : | Front Immunol |
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Главные авторы: | , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Frontiers Media S.A.
2016
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5081367/ https://ncbi.nlm.nih.gov/pubmed/27833610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00449 |
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