Paradoxical enhancement of atherosclerosis by probucol treatment in apolipoprotein E-deficient mice.

Dietary administration of probucol (0.5%, wt/wt) efficiently reduced total plasma cholesterol levels in apolipoprotein E-deficient mice (apoE-/-) by 40%, with decreases in high density lipoprotein (HDL) and apoAI by 70 and 50%, respectively. Paradoxically, however, aortic atherosclerotic plaques in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhang, S H, Reddick, R L, Avdievich, E, Surles, L K, Jones, R G, Reynolds, J B, Quarfordt, S H, Maeda, N
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1997
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC508136/
https://ncbi.nlm.nih.gov/pubmed/9185508
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