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MCP-1 protects mice in lethal endotoxemia.

The overzealous production of proinflammatory cytokines in sepsis can result in shock, multiorgan dysfunction, and even death. In this study, we assessed the role of monocyte chemoattractant protein-1 (MCP-1) as a mediator of sepsis in endotoxin-challenged mice. Intraperitoneal administration of LPS...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Zisman, D A, Kunkel, S L, Strieter, R M, Tsai, W C, Bucknell, K, Wilkowski, J, Standiford, T J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508132/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9185504/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119475
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