Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxemia and severe gram-negative infections.

Lipoproteins can bind lipopolysaccharide (LPS) and decrease the LPS-stimulated production of pro-inflammatory cytokines. We investigated the effect of increased plasma concentrations of low-density-lipoproteins (LDL) on survival and cytokine production after a lethal challenge with either LPS or liv...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Netea, M G, Demacker, P N, Kullberg, B J, Boerman, O C, Verschueren, I, Stalenhoef, A F, van der Meer, J W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617867/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118556
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