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Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxemia and severe gram-negative infections.

Lipoproteins can bind lipopolysaccharide (LPS) and decrease the LPS-stimulated production of pro-inflammatory cytokines. We investigated the effect of increased plasma concentrations of low-density-lipoproteins (LDL) on survival and cytokine production after a lethal challenge with either LPS or liv...

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Dettagli Bibliografici
Autori principali: Netea, M G, Demacker, P N, Kullberg, B J, Boerman, O C, Verschueren, I, Stalenhoef, A F, van der Meer, J W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC507194/
https://ncbi.nlm.nih.gov/pubmed/8617867
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