Epithelial to Stromal Re-Distribution of Primary Cilia during Pancreatic Carcinogenesis

BACKGROUND: The Hedgehog (HH) pathway is a mediator in pancreatic ductal adenocarcinoma (PDAC). Surprisingly, previous studies suggested that primary cilia (PC), the essential organelles for HH signal transduction, were lost in PDAC. The aim of this study was to determine the presence of PC in human...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Schimmack, Simon, Kneller, Sarah, Dadabaeva, Nigora, Bergmann, Frank, Taylor, Andrew, Hackert, Thilo, Werner, Jens, Strobel, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081192/
https://ncbi.nlm.nih.gov/pubmed/27783689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164231
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