Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione

Humanin (HN) is a small mitochondrial-encoded peptide with neuroprotective properties. We have recently shown protection of retinal pigmented epithelium (RPE) cells by HN in oxidative stress; however, the effect of HN on endoplasmic reticulum (ER) stress has not been evaluated in any cell type. Our...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Matsunaga, Douglas, Sreekumar, Parameswaran G., Ishikawa, Keijiro, Terasaki, Hiroto, Barron, Ernesto, Cohen, Pinchas, Kannan, Ram, Hinton, David R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081188/
https://ncbi.nlm.nih.gov/pubmed/27783653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165150
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