Inactivation of Streptococcus pyogenes extracellular cysteine protease significantly decreases mouse lethality of serotype M3 and M49 strains.

Cysteine proteases have been implicated as important virulence factors in a wide range of prokaryotic and eukaryotic pathogens, but little direct evidence has been presented to support this notion. Virtually all strains of the human bacterial pathogen Streptococcus pyogenes express a highly conserve...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Lukomski, S, Sreevatsan, S, Amberg, C, Reichardt, W, Woischnik, M, Podbielski, A, Musser, J M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508102/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9169486/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119445
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