Inactivation of Streptococcus pyogenes extracellular cysteine protease significantly decreases mouse lethality of serotype M3 and M49 strains.

Cysteine proteases have been implicated as important virulence factors in a wide range of prokaryotic and eukaryotic pathogens, but little direct evidence has been presented to support this notion. Virtually all strains of the human bacterial pathogen Streptococcus pyogenes express a highly conserve...

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Autori principali: Lukomski, S, Sreevatsan, S, Amberg, C, Reichardt, W, Woischnik, M, Podbielski, A, Musser, J M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC508102/
https://ncbi.nlm.nih.gov/pubmed/9169486
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