Mesenchymal stromal cells derived from cervical cancer produce high amounts of adenosine to suppress cytotoxic T lymphocyte functions

BACKGROUND: In recent years, immunomodulatory mechanisms of mesenchymal stem/stromal cells (MSCs) from bone marrow and other “classic” sources have been described. However, the phenotypic and functional properties of tumor MSCs are poorly understood. The aim of this study was to analyze the immunosu...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: de Lourdes Mora-García, María, García-Rocha, Rosario, Morales-Ramírez, Omar, Montesinos, Juan José, Weiss-Steider, Benny, Hernández-Montes, Jorge, Ávila-Ibarra, Luis Roberto, Don-López, Christian Azucena, Velasco-Velázquez, Marco Antonio, Gutiérrez-Serrano, Vianey, Monroy-García, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080842/
https://ncbi.nlm.nih.gov/pubmed/27782859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1057-8
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