Mesenchymal stromal cells derived from cervical cancer produce high amounts of adenosine to suppress cytotoxic T lymphocyte functions

BACKGROUND: In recent years, immunomodulatory mechanisms of mesenchymal stem/stromal cells (MSCs) from bone marrow and other “classic” sources have been described. However, the phenotypic and functional properties of tumor MSCs are poorly understood. The aim of this study was to analyze the immunosu...

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Bibliographische Detailangaben
Veröffentlicht in:J Transl Med
Hauptverfasser: de Lourdes Mora-García, María, García-Rocha, Rosario, Morales-Ramírez, Omar, Montesinos, Juan José, Weiss-Steider, Benny, Hernández-Montes, Jorge, Ávila-Ibarra, Luis Roberto, Don-López, Christian Azucena, Velasco-Velázquez, Marco Antonio, Gutiérrez-Serrano, Vianey, Monroy-García, Alberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080842/
https://ncbi.nlm.nih.gov/pubmed/27782859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1057-8
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