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Human recombinant apolipoprotein E redirects lipopolysaccharide from Kupffer cells to liver parenchymal cells in rats In vivo.

Chylomicrons have been shown to protect mice and rats against a lethal dose of lipopolysaccharide and may serve as a therapeutic means to protect against endotoxemia. However, the requisite of isolation from human lymph hampers pharmaceutical application. Recently, we developed recombinant chylomicr...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Rensen, P C, Oosten, M, Bilt, E, Eck, M, Kuiper, J, Berkel, T J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508084/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9153287/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119427
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