Association between Mutation and Expression of TP53 as a Potential Prognostic Marker of Triple-Negative Breast Cancer

PURPOSE: TP53, the most frequently mutated gene in breast cancer, is more frequently altered in HER2-enriched and basal-like breast cancer. However, no studies have clarified the role of TP53 status as a prognostic and predictive marker of triple-negative breast cancer (TNBC). MATERIALS AND METHODS:...

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Vydáno v:Cancer Res Treat
Hlavní autoři: Kim, Ji-Yeon, Park, Kyunghee, Jung, Hae Hyun, Lee, Eunjin, Cho, Eun Yoon, Lee, Kwang Hee, Bae, Soo Youn, Lee, Se Kyung, Kim, Seok Won, Lee, Jeong Eon, Nam, Seok Jin, Ahn, Jin Seok, Im, Young-Hyuck, Park, Yeon Hee
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Cancer Association 2016
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080805/
https://ncbi.nlm.nih.gov/pubmed/26910472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2015.430
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